{"id":2061,"date":"2021-09-02T13:04:45","date_gmt":"2021-09-02T13:04:45","guid":{"rendered":"https:\/\/mewigen.de\/?page_id=2061"},"modified":"2021-12-08T16:53:53","modified_gmt":"2021-12-08T16:53:53","slug":"microsatellite","status":"publish","type":"page","link":"https:\/\/mewigen.de\/index.php\/microsatellite\/","title":{"rendered":"Microsatellite Analyses"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"2061\" class=\"elementor elementor-2061\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9c61932 elementor-section-content-middle animated-slow elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9c61932\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;none&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cb590bc\" data-id=\"cb590bc\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-072942a elementor-widget elementor-widget-heading\" data-id=\"072942a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">MEWIGEN Microsatellite Analysis<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9682deb elementor-widget elementor-widget-heading\" data-id=\"9682deb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">In order to estimate the probability of mutations in mismatch repair genes in patients with Lynch syndrome-associated cancers.<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-87d2175 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"87d2175\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6a44d1d\" data-id=\"6a44d1d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-91065af elementor-widget elementor-widget-spacer\" data-id=\"91065af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-804d0af elementor-widget elementor-widget-heading\" data-id=\"804d0af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Microsatellite Analysis<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d59d8d8 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"d59d8d8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/mewigen.de\/wp-content\/uploads\/2021\/09\/Submission_Form_MEWIGEN.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"icon icon-download\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Download Submission Form<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a49e1de elementor-widget elementor-widget-spacer\" data-id=\"a49e1de\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-23798a3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"23798a3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a7d76a9\" data-id=\"a7d76a9\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a98ab45 elementor-widget elementor-widget-text-editor\" data-id=\"a98ab45\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>We offer a PCR-based analysis&nbsp;of the Bethesda markers in tumor tissue and corresponding normal tissue. High microsatellite instability (MSI-H) indicate mismatch repair (MMR) deficiency based either on somatic or on germline mutations in respective genes, whereby the latter proves a Lynch syndrome.&nbsp;<\/p>\n<p style=\"text-align: center;\"><span style=\"color: #ff8200;\"><span style=\"color: #000000;\">Method:<\/span> <\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"color: rgb(100, 149, 237);\">Fluorescence-based fragment length analyses<\/span><br><\/p>\n<p style=\"text-align: center;\">Turnaround time:<\/p>\n<p style=\"text-align: center;\"><span style=\"color: #6495ed;\">3 weeks<\/span><\/p>\n<p style=\"text-align: center;\">Specimen requirements:<\/p>\n<p style=\"text-align: center;\"><span style=\"color: #6495ed;\">DNA from tumor tissue and, if possible, from paired normal tissue<br><\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"text-align: justify; color: var( --e-global-color-text ); font-size: 1rem;\">Please contact us beforehand if you want us to isolate DNA from tumor and\/or normal tissue.<\/span><br><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bfe65b6 elementor-widget elementor-widget-spacer\" data-id=\"bfe65b6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>MEWIGEN Microsatellite Analysis In order to estimate the probability of mutations in mismatch repair genes in patients with Lynch syndrome-associated cancers. Microsatellite Analysis Download Submission Form We offer a PCR-based analysis&nbsp;of the Bethesda markers in tumor tissue and corresponding normal tissue. High microsatellite instability (MSI-H) indicate mismatch repair (MMR) deficiency based either on somatic or [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2061","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mewigen.de\/index.php\/wp-json\/wp\/v2\/pages\/2061","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mewigen.de\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mewigen.de\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mewigen.de\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mewigen.de\/index.php\/wp-json\/wp\/v2\/comments?post=2061"}],"version-history":[{"count":38,"href":"https:\/\/mewigen.de\/index.php\/wp-json\/wp\/v2\/pages\/2061\/revisions"}],"predecessor-version":[{"id":3705,"href":"https:\/\/mewigen.de\/index.php\/wp-json\/wp\/v2\/pages\/2061\/revisions\/3705"}],"wp:attachment":[{"href":"https:\/\/mewigen.de\/index.php\/wp-json\/wp\/v2\/media?parent=2061"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}